I will denote the given system as,
$$
G(s) = \frac{20(1+s)^2}{(1+\frac{s}{2})(1+\frac{s}{10})}
$$
The input or reference signal to the closed loop will be denoted by $R(s)$ and the output by $Y(s)$. The controller will initially be denoted by $H(s)$, while in this case it is equal to $K$. The block diagram of the closed loop system can then be drawn as,

With its transfer function from input to output equal to,
$$
\frac{Y(s)}{R(s)} = \frac{G(s)}{1 + H(s) G(s)}.
$$
For root locus analysis you want to find the poles of this transfer function as function of $H(s)$. The poles can be found by solving when the denominator is equal to zero. However the denominator (and numerator) are polynomials of $s$, so can't be fractions themselves. In order to ensure this I will slit $G(s)$ up in to two parts, its numerator, $G_n(s)$, and denominator, $G_d(s)$. The same can be done for $H(s)$. The resulting transfer function can then be written as,
$$
\frac{Y(s)}{R(s)} = \frac{\frac{G_n(s)}{G_d(s)}}{1 + \frac{H_n(s)}{H_d(s)} \frac{G_n(s)}{G_d(s)}} = \frac{H_d(s) G_n(s)}{H_d(s) G_d(s) + H_n(s) G_n(s)}.
$$
As stated before, in this case $H(s)$ is equal to $K$, thus $H_d(s)$ is equal to one. By substituting in $K$ for $H_n(s)$ and the two polynomials, from this first equation, for $G_n(s)$ and $G_d(s)$, then the following expression can be obtained,
$$
\frac{Y(s)}{R(s)} = \frac{20(1+s)^2}{(1+\frac{s}{2})(1+\frac{s}{10}) + 20K(1+s)^2}.
$$
The resulting denominator is a second order polynomial, so solving for the poles yields two solutions, which can be simplified to,
$$
p=-\frac{400 K \pm 4 \sqrt{1 - 225 K} + 6}{400 K + 1}.
$$
For $K=-\frac{1}{400}$ the limits of both $p$ are $\pm\infty$ depending if you approach that value from the left or the right. Thus near $K=-\frac{1}{400}$ there will be values for the poles of the closed loop transfer function which will have a positive real values.