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Feb 11, 2022 at 11:53 history edited Tom Wenseleers CC BY-SA 4.0
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Aug 20, 2019 at 11:26 comment added Tom Wenseleers One can also use Poisson 1/variance weights btw in the nnls() step, using weights = 1/(y+1); nnls(A=bandedM*sqrt(weights), b=y*sqrt(weights)) - that would better take into account the fact that we have Poisson noise here. [It would become similar to Richardson-Lucy deconvolution then, but would then use a closed-form single step weighted least squares approximation; if need be the variance weights could also be further updated based on the fitted values using an IRLS algorithm, like the ones used to solve generalized linear models, as in bwlewis.github.io/GLM/]
Aug 20, 2019 at 11:20 comment added Tom Wenseleers Well it's quite easy really - just install R and RStudio, and step through it line by line using CTRL-ENTER so that you can see what each line does :-)
Aug 20, 2019 at 4:52 comment added Royi I wish the code was MATLAB so I can understand it :-).
S Jul 2, 2019 at 21:44 history suggested Glorfindel CC BY-SA 4.0
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Jul 2, 2019 at 18:31 review Suggested edits
S Jul 2, 2019 at 21:44
Jan 26, 2019 at 12:25 history edited Tom Wenseleers CC BY-SA 4.0
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Jan 14, 2019 at 14:48 comment added A_A I think that it would be worth updating the question with more information about what you were trying to achieve (e.g. your comment towards Cedron Dawg) and how the solution you provided fits that particular use case. If you added a few lines in the intro of your Q and the intro of your A, that would make this a very valuable post in general. All the best.
Jan 12, 2019 at 15:39 history edited Tom Wenseleers CC BY-SA 4.0
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Jan 12, 2019 at 14:10 history edited Tom Wenseleers CC BY-SA 4.0
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Jan 11, 2019 at 19:28 history edited Peter K. CC BY-SA 4.0
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Jan 11, 2019 at 16:42 history edited Tom Wenseleers CC BY-SA 4.0
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Jan 10, 2019 at 22:51 history edited Tom Wenseleers CC BY-SA 4.0
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Jan 10, 2019 at 22:00 history edited Tom Wenseleers CC BY-SA 4.0
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Jan 10, 2019 at 21:54 history edited Tom Wenseleers CC BY-SA 4.0
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Jan 10, 2019 at 21:18 history edited Tom Wenseleers CC BY-SA 4.0
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Jan 10, 2019 at 21:05 comment added Peter K. Looks pretty good to me! Nicely done.
Jan 10, 2019 at 20:25 history edited Tom Wenseleers CC BY-SA 4.0
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Jan 10, 2019 at 20:17 history edited Tom Wenseleers CC BY-SA 4.0
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Jan 10, 2019 at 20:01 history edited Tom Wenseleers CC BY-SA 4.0
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Jan 10, 2019 at 19:50 history edited Tom Wenseleers CC BY-SA 4.0
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Jan 10, 2019 at 19:30 history answered Tom Wenseleers CC BY-SA 4.0